Current vascular research at LUHFT focusses on Abdominal Aortic Aneurysms (AAAs), stent grafts (for AAA and lower limb), and wound healing. Importantly, our research also assesses the clinical and cost effectiveness of current and novel techniques or equipment to inform future clinical practice. Below is more information about the research studies being conducted within our vascular department.

Current research:

A comparison study of open surgery, endovascular surgery, and medical management for complex AAAs.

This study is comprised of two arms:

1) Quality of life in operated versus medically managed patients, assessed by questionnaires

2) Routinely collected data, including stent graft complications, secondary interventions, and mortality within the peri-operative period (up to 30 days post-surgery) and long term (up to five years post-surgery).

Records device specific outcomes in AAA patients treated with certain stent grafts. Patients are followed up for up to five years post-surgery to assess the technical success of the operation, stent graft complications, secondary interventions and mortality.

Aims to evaluate the procedure time and resource use in surgeries using a novel artificial intelligence device (Cydar EV) system versus standard treatment. Patients are followed up for five year post-surgery to assess the technical success of the operation, stent graft complications, secondary interventions and quality of life. This data will be used to calculate overall clinical, technical and cost-effectiveness of using Cydar EV compared to standard treatment in endovascular surgery.

Evaluates the safety and effectiveness of the commercially available LimFlow device in patients at risk of below knee amputation. Patients are followed up for 12 months post-surgery, and assessed for amputation free survival, wound healing, quality of life, functionality of the LimFlow stent graft and overall technical and procedural success.

A randomised controlled trial to compare the time to wound healing and cost effectiveness of negative pressure therapy versus standard dressings in treating surgical wounds that have been left open to heal.